2  HLA Imputation Programs

Table

Name	Programming Language	Input Data	Output	Reference
SNP2HLA	Command line interface	PLINK binary format	HLA class I and II alleles	Jia et al. (2013)
HIBAG	R	Plink binary format	HLA class I and II alleles	Zheng et al. (2014)

Jia, Xiaoming, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J. Concannon, Stephen S. Rich, Soumya Raychaudhuri, and Paul I. W. de Bakker. 2013. “Imputing amino acid polymorphisms in human leukocyte antigens.” PloS One 8 (6): e64683. https://doi.org/10.1371/journal.pone.0064683.

Zheng, X., J. Shen, C. Cox, J. C. Wakefield, M. G. Ehm, M. R. Nelson, and B. S. Weir. 2014. “HIBAG–HLA genotype imputation with attribute bagging.” The Pharmacogenomics Journal 14 (2): 192–200. https://doi.org/10.1038/tpj.2013.18.