Human Leukocyte Antigens

Background

HLA is located on chromosome 6 in the Major Histocompatibility Complex (MHC).

HLA Class I

HLA class I molecules are expressed by healthy nucleated cells.

HLA Class II

HLA class II molecules are expressed by professional antigen-presenting cells (APC)–dendritic cells, macrophages, and B cells.

HLA Nomenclature

HLA naming

HLA naming